Q. Why was DNA Capsule started?
A. Both my father and my husband’s mother recently passed away from cancer. We realized the importance of saving DNA, with both of our loved ones choosing to be cremated, thus destroying valuable genetic data. Our company’s purpose is to give people the ability to save their DNA at home, which contains vital information about a person’s ancestry that could benefit future generations.
Q. How can I save my DNA for future use, either by me or my children?
A. DNA Capsule has developed an at home storage container, which contains several drops of your blood that is mixed and dried with a matrix that draws out all moisture. The container is sealed and can be analyzed at Sorenson Genomics for genetic testing.
Q. What is gene testing? How does it work?
A. Gene tests involve direct examination of the DNA molecule itself. The scientist scan a patient’s DNA sample for mutated sequences. Researchers design short pieces of DNA called probes, whose sequences are complementary to the mutated sequences. These probes will seek their complement among the three billion base pars of an individual’s genome. If the mutated sequence is present in the patient’s genome, the probe will bind to it and flag the mutation.
Q. Why Does DNA Capsule use blood samples rather than Buccal samples(saliva)?
A. The National Cancer Institute did a study on long-term storage and recovery of buccal cell DNA. It concluded blood can be stored for long periods with adequate DNA recovery, but information on storage and successful recovery of buccal cell DNA beyond two years is not known. Stored buccal cells do not consistently provide sufficient quantities or quality of human DNA for genotyping or whole genome amplification, while blood stored provides high quality and quantity of DNA. The testing facility is able to run multiple tests on one sample.
Q. Is storing my sample going to be a problem?
A. You can store your sample anywhere you like at room temperature. The sample needs to remain sealed until the family chooses to have it analyzed. We recommend Sorenson Genomics for genetic testing.
Q. How many times can my sample be tested because I have more than one child?
A. Since the saved DNA sample is stored whole blood, multiple tests can be run on one sample.
Q. For what disease are gene tests available?
A. Currently, more than 1,000 genetic tests are available. In the future the tests will be more reliable, prevalent, and cheaper. The current list available for DNA based gene tests are as follows: